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Ethyl Caffeate
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Ethyl Caffeate图片
CAS NO:102-37-4

Ethyl Caffeate 是一种从 Bidens pilosa 分离的天然酚类化合物。Ethyl Caffeate 在体外或在小鼠皮肤中抑制 NF-κB 活化及其下游炎症介质，诱导型一氧化氮合酶 (iNOS)，环氧合酶 2 (COX-2) 和前列腺素 E2 (PGE2)。
Cas No.102-37-4
别名咖啡酸乙酯
Canonical SMILESO=C(OCC)/C=C/C1=CC=C(O)C(O)=C1
分子式C11H12O4
分子量208.21
溶解度DMSO: 250 mg/mL (1200.71 mM)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].

Ethyl Caffeate markedly suppresses the lipopolysaccharide (LPS)-induced nitric oxide (NO) production with IC50 of 5.5 μg/ml[1].

[1]. Chiang YM, et al. Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. Br J Pharmacol. 2005 Oct;146(3):352-63.

 
 
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