DS-1001b 是一种有效的 IDH-1 (异柠檬酸脱氢酶-1) 突变体抑制剂，详细信息请参考专利文献 WO2016052697A1 中的例 168。
| Cas No. | 1898207-64-1 |
| Canonical SMILES | CC(C)(N)C.O=C(N1C2=CC=CC(/C=C/C(O)=O)=C2C(C)=C1)C3=C(C(C)(F)C)ON=C3C4=C(C=C(Cl)C=C4Cl)Cl |
| 分子式 | C29H29Cl3FN3O4 |
| 分子量 | 608.92 |
| 溶解度 | DMSO: 29 mg/mL (47.63 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | DS-1001b is a mutant IDH-1 (Isocitrate Dehydrogenase-1) inhibitor extracted from patent WO2016052697A1, Example 168, and has antitumor activity[1]. [1]. Zhao Yizhaiteng, et al. Isoxazole derivative as mutated isocitrate dehydrogenase 1 inhibitor. WO2016052697A1. |
