Bufexamac 是一种 IIB 类组蛋白去乙酰化酶（HDAC6 和 HDAC10）抑制剂，用作抗炎剂。
| Cas No. | 2438-72-4 |
| 别名 | 丁苯羟酸; Bufexamic acid |
| 化学名 | 2-(4-butoxyphenyl)-N-hydroxyacetamide |
| Canonical SMILES | CCCCOC1=CC=C(C=C1)CC(=O)NO |
| 分子式 | C12H17NO3 |
| 分子量 | 223.27 |
| 溶解度 | ≥ 11.2mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Bufexamac is a class IIB histone deacetylases (HDAC6 and HDAC10) inhibitor used as an anti-inflammatory agent. References:
[1]. Bantscheff, M., et al., Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. Nat Biotechnol, 2011. 29(3): p. 255-65.
[2]. Kranke, B., et al., Epidemiological significance of bufexamac as a frequent and relevant contact sensitizer. Contact Dermatitis, 1997. 36(4): p. 212-5. |
