Methylophiopogonanone B,高异二氢黄酮,从麦冬的根中提取,具有很高的抗氧化能力。Methylophiopogonanone B 增加 GTP-Rho 并通过 Rho 信号传导途径起作用,Methylophiopogonanone B 通过肌动蛋白细胞骨架重组诱导细胞形态变化,包括树突收缩和应力纤维形成。
Cas No. | 74805-91-7 |
别名 | 甲基麦冬黄烷酮B |
Canonical SMILES | O=C1[C@H](CC2=CC=C(OC)C=C2)COC3=C(C)C(O)=C(C)C(O)=C13 |
分子式 | C19H20O5 |
分子量 | 328.36 |
溶解度 | DMSO: 10 mM |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas, shows high antioxidant ability[1]. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation[2]. [1]. Wang Y, et al. Homoisoflavonoids and the Antioxidant Activity of Ophiopogon japonicus Root.
[2]. Ito Y, et al. A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization. Mol Cell Biochem. 2007 Mar;297(1-2):121-9. Epub 2006 Oct 7. |