Chlortetracyclinehydrochloride(7-Chlorotetracyclinehydrochloride)是一种特异性的有效钙离子载体抗生素,抑制氨酰tRNA结合到核糖体。
Cas No. | 64-72-2 |
别名 | 盐酸金霉素; 7-Chlorotetracycline hydrochloride |
Canonical SMILES | O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4Cl)N.[H]Cl |
分子式 | C22H24Cl2N2O8 |
分子量 | 515.34 |
溶解度 | ≥ 25.8 mg/mL in DMSO with gentle warming, ≥ 12.88 mg/mL in Water with ultrasonic and warming |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is a specific and potent calcium ionophore antibiotic, inhibits binding of aminoacyl-tRNA to ribosomes. [1]. Elmund GK, et al. Role of excreted chlortetracycline in modifying the decomposition process in feedlot waste. Bull Environ Contam Toxicol. 1971 Mar-Apr;6(2):129-32.
[2]. Saling PM, et al. Mouse gamete interactions during fertilization in vitro. Chlortetracycline as a fluorescent probe for the mouse sperm acrosome reaction. J Cell Biol. 1979 Dec;83(3):544-55. |