PKN1/2-IN-1 是一种有效的细胞渗透剂和选择性 PKN2 (PRK2) 抑制剂(IC50=16 nM；Ki=8 nM)。
| Cas No. | 942425-34-5 |
| 分子式 | C14H15N3O |
| 分子量 | 241.29 |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | PKN1/2-IN-1 is a potent, cell penetrant and selective PKN2 (PRK2) inhibitor (IC50=16 nM; Ki=8 nM)[1]. [1]. Scott F, et al. Development of dihydropyrrolopyridinone-based PKN2/PRK2 chemical tools to enable drug discovery. Bioorg Med Chem Lett. 2022;60:128588. |
