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BNC375
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BNC375图片
CAS NO:1557240-80-8

BNC375 是一种口服有效的选择性 α7nAChRs I 型正向变构调节剂,EC50 为 1.9 μM。
Cas No.1557240-80-8
Canonical SMILESClC1=CC=C(OC)C(NC[C@H]2C(C)(C)[C@@H]2C3=CC=C(S(N)(=O)=O)C=C3)=C1
分子式C19H23ClN2O3S
分子量394.92
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

BNC375 is a potent, selective, and orally available type I positive allosteric modulator of α7 nAChRs with an EC50 of 1.9 μM[1].

[1]. Andrew J. Harvey, et al. Discovery of BNC375, a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs. Cite This:ACS Med. Chem. Lett.2019105754-760.

 
 
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