NLRP3/AIM2-IN-3是一种抑制NLRP3 和AIM2 炎症小体活化并具有物种差异的独特分子，其IC50值为0.077±0.008 μM。
| Cas No. | 1787787-60-3 |
| 分子式 | C16H14N2O2 |
| 分子量 | 266.29 |
| 溶解度 | DMSO : 250 mg/mL (938.83 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | NLRP3/AIM2-IN-3 is a unique molecule that inhibits the activation of NLRP3 and AIM2 inflammatory bodies and has species differences. Its IC 50 value is 0.077 ± 0.008 μ M。 [1]. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194. |
