Procainamide HCl 是一种抗心律失常药,用于治疗心律失常;诱导快速阻断心肌的蝙蝠鱼毒素 (BTX) 激活的钠通道,并作为长门控关闭的拮抗剂。
Cas No. | 614-39-1 |
别名 | 盐酸普鲁卡因胺 |
化学名 | 4-amino-N-[2-(diethylamino)ethyl]benzamide;hydrochloride |
Canonical SMILES | CCN(CC)CCNC(=O)C1=CC=C(C=C1)N.Cl |
分子式 | C13H22ClN3O |
分子量 | 271.79 |
溶解度 | ≥ 13.65mg/mL in DMSO |
储存条件 | 4°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Procainamide hydrochloride is an anti-arrhythmic agent and is used to treat cardiac arrhythmia; induces rapid block of the batrachotoxin(BTX)-activated sodium channels of the heart muscle and acts as antagonist to long gating closures. References: [1]. Zamponi GW, et al. Dual actions of procainamide on batrachotoxin-activated sodium channels: open channel block and prevention of inactivation. Biophys J. 1993 Dec;65(6):2324-34. [2]. http://en.wikipedia.org/wiki/Procainamid |