单链 DNA 中的 5-Methyl-2'-deoxycytidine 可以顺式作用以发出从头 DNA 甲基化信号。
| Cas No. | 838-07-3 |
| 别名 | 5-甲基-2'-脱氧胞苷,5-Methyldeoxycytidine |
| Canonical SMILES | O=C(N=C(N)C(C)=C1)N1[C@H]2C[C@H](O)[C@@H](CO)O2 |
| 分子式 | C10H15N3O4 |
| 分子量 | 241.2 |
| 溶解度 | DMF: 5 mg/ml,DMSO: 20 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation[1][2]. References:
[1]. Christman JK, et al. 5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation. Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7347-51.
[2]. Testillano PS, et al. The 5-methyl-deoxy-cytidine (5mdC) localization to reveal in situ the dynamics of DNA methylation chromatin pattern in a variety of plant organ and tissue cells during development. Physiol Plant. 2013 Sep;149(1):104-13. |
