Zaloglanstat (ISC-27864) 是 mPGES-1 的抑制剂，可用于哮喘、骨关节炎、类风湿性关节炎、急性或慢性疼痛和神经退行性疾病等的研究。
| Cas No. | 1513852-12-4 |
| 别名 | ISC-27864; GRC-27864 |
| 分子式 | C21H20ClF3N4O2 |
| 分子量 | 452.86 |
| 溶解度 | DMSO : 250 mg/mL (552.05 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Zaloglanstat (ISC-27864) is the inhibitor of the microsomal prostaglandin E synthase-1 (mPGES-1), and can be used to study asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases, etc[1]. [1]. Di Micco S, Terracciano S, Ruggiero D, Potenza M, Vaccaro MC, Fischer K, Werz O, Bruno I, Bifulco G. Identification of 2-(thiophen-2-yl)acetic Acid-Based Lead Compound for mPGES-1 Inhibition. Front Chem. 2021 May 7;9:676631. |
