Meglutol (Dicrotalic acid) 是一种抗血脂剂，可降低胆固醇、甘油三酯、血清 β-脂蛋白和磷脂，并抑制羟甲基戊二酰辅酶 A 还原酶的活性，羟甲基戊二酰辅酶 A 还原酶是胆固醇生物合成中的限速酶。
| Cas No. | 503-49-1 |
| 别名 | 3-羟基-3-甲基谷氨酸,Dicrotalic acid; 3-Hydroxy-3-methylglutaric acid |
| Canonical SMILES | O=C(O)CC(C)(O)CC(O)=O |
| 分子式 | C6H10O5 |
| 分子量 | 162.14 |
| 溶解度 | DMSO: 250 mg/mL (1541.88 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol. |
