PTI-428 (PTI-428) 是一种特异性囊性纤维化跨膜电导调节器 (CFTR) 放大器。
| Cas No. | 1953130-87-4 |
| 别名 | PTI-428 |
| Canonical SMILES | O=C(C1=CC(C2=CC=CC=C2)=NO1)N[C@H]3C[C@H](C4=NN=C([C@H](O)C)O4)C3 |
| 分子式 | C18H18N4O4 |
| 分子量 | 354.36 |
| 溶解度 | DMSO : 250 mg/mL (705.50 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | PTI-428 is a specific cystic fibrosis transmembrane conductance regulator (CFTR) amplifier[1].
CFTR[1] [1]. Mijnders M, et al. Correcting CFTR folding defects by small-molecule correctors to cure cystic fibrosis. Curr Opin Pharmacol. 2017 Jun;34:83-90. |
