L-erythro Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and D-threo sphinganine.
| Cas No. | 6036-76-6 |
| 别名 | L-苏式-二氢鞘胺醇 |
| Canonical SMILES | OC[C@@H](N)[C@@H](O)CCCCCCCCCCCCCCC |
| 分子式 | C18H39NO2 |
| 分子量 | 301.5 |
| 溶解度 | Chloroform: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | L-erythro Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and D-threo sphinganine . It induces autophagy in HCT116 cells when used at a concentration of 12 μM. L-erythro Sphinganine induces cell cycle arrest of 7R4-LCB1 yeast cells. It is metabolized via sphinganine N-acyltransferase and sphinganine kinase in vivo in rat liver. |
