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(±)-ML 209
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(±)-ML 209图片
CAS NO:1334526-14-5
包装与价格:
包装价格(元)
10mg询价
50mg询价

An RORγt antagonist
Cas No.1334526-14-5
Canonical SMILESCOC1=CC(OC)=C(C(O)=C1)C(C2=CC=C3OCOC3=C2)CC(N4C[C@@H](C[C@@H](C4)C)C)=O
分子式C25H31NO6
分子量441.52
溶解度DMSO: 100 mM
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

RORγt inverse agonist (IC50 = 460 nM). Suppresses Th17 cell differentiation and IL17A expression in vitro. Does not suppress transcription of RORα. Minimal activity displayed on ERα, LXRα and thyroid hormone receptors (IC50 values >4.4 μM).

 
 
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