Inupadenant (EOS-850) 是一种具有口服活性的，高选择性 A2A 受体拮抗剂。Inupadenant 不能透过血脑屏障。Inupadenant 具有抗肿瘤活性。
| Cas No. | 2246607-08-7 |
| 别名 | EOS-850 |
| 分子式 | C25H26F2N8O4S2 |
| 分子量 | 604.65 |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Inupadenant is an orally active, highly selective A2A receptor antagonist. Inupadenant is not brain-penetrant. Inupadenant has potent anti-tumor activity[1]. [1]. Laurence Buisseret, et al. Phase 1 trial of the adenosine A2Areceptor antagonist inupadenant (EOS-850): Update on tolerability, and antitumor activity potentially associated with the expression of the A2A receptor within the tumor. Journal of Clinical Oncology. Volume 39, Issue 15_suppl. |
