首页 蛋白库 基因库 产品 会员服务
位置：首页 > 产品库 > 3&rsquo-Azido-2&rsquo,3&rsquo-dideoxyuridine
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
3&rsquo-Azido-2&rsquo,3&rsquo-dideoxyuridine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
3&rsquo-Azido-2&rsquo,3&rsquo-dideoxyuridine图片
CAS NO:84472-85-5
包装与价格：
包装价格(元)
5mg询价
10mg询价
25mg询价
50mg询价

An antiviral nucleoside analog
Cas No.84472-85-5
别名3'-叠氮-2',3'-双脱氧尿苷
Canonical SMILESO=C1N([C@@]2([H])C[C@@H]([C@H](O2)CO)N=[N+]=[N-])C=CC(N1)=O
分子式C9H11N5O4
分子量253.2
溶解度DMF: 2 mg/ml,DMSO: 2 mg/ml,Ethanol: insol,PBS (pH 7.2): 1 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3’-Azido-2’,3’-dideoxyuridine (AZddU) is an antiviral nucleoside analog.1It is phosphorylated by thymidine kinase.2AZddU inhibits cytopathogenicity induced by HIV or Moloney sarcoma virus (MSV) in MT-4 cells (EC50s = 0.36 and 15 µM, respectively).1

1.Balzarini, J., Baba, M., Pauwels, R., et al.Anti-retrovirus activity of 3’-fluoro- and 3’-azido-substituted pyrimidine 2’,3’-dideoxynucleoside analoguesBiochem. Pharmacol.37(14)2847-2856(1988) 2.Eriksson, B.F., Chu, C.K., and Schinazi, R.F.Phosphorylation of 3’-azido-2’,3’-dideoxyuridine and preferential inhibition of human and simian immunodeficiency virus reverse transcriptases by its 5’-triphosphateAntimicrob. Agents Chemother.33(10)1729-1734(1989)

 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2025