BC-1471 是一种 STAM 结合蛋白(STAMBP)去泛素酶抑制剂。BC-1471 抑制 NALP7(NACHT, LRR 和 PYD 结构域蛋白 7)的炎症小体活性。
Cas No. | 896683-84-4 |
分子式 | C27H32N4O4S |
分子量 | 508.63 |
溶解度 | DMSO : 50 mg/mL (98.30 mM; Need ultrasonic) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | BC-1471 is a STAM-binding protein (STAMBP) deubiquitinase inhibitor. BC-1471 inhibits NALP7 (NACHT, LRR and PYD domains-containing protein 7) inflammasome activity[1]. [1]. Bednash JS, et al. Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity. Nat Commun. 2017 May 11;8:15203. |