Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) 是一种有效的外用糖皮质激素。
| Cas No. | 74050-20-7 |
| 别名 | 醋丙氢可的松,Hydrocortisone 17-propionate 21-acetate |
| Canonical SMILES | C[C@@]12[C@](C(COC(C)=O)=O)(OC(CC)=O)CC[C@@]1([H])[C@@]3([H])[C@]([C@@]4(C(CC3)=CC(CC4)=O)C)([H])[C@H](C2)O |
| 分子式 | C26H36O7 |
| 分子量 | 460.6 |
| 溶解度 | DMF: 3 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): insol |
| 储存条件 | -20буC |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Hydrocortisone aceponate is a corticosteroid.1,2Topical application of hydrocortisone aceponate (0.0584%) reduces lesion size and pruritis in cats with allergic dermatitis.1It also induces remission and increases time to relapse in dogs with spontaneous atopic dermatitis.2Formulations containing hydrocortisone aceponate have been used in the treatment of veterinary dermatoses. 1.Schmidt, V., Buckley, L.M., McEwan, N.A., et al.Efficacy of a 0.0584% hydrocortisone aceponate spray in presumed feline allergic dermatitis: An open label pilot studyVet. Dermatol.23(1)11-16(2012)
2.LourenÇo, A.M., Schmidt, V., Braz, B.S., et al.Efficacy of proactive long-term maintenance therapy of canine atopic dermatitis with 0.0584% hydrocortisone aceponate spray: A double-blind placebo controlled pilot studyVet. Dermatol.27(2)88e25-92e25(2016) |
