JH-XVI-178 是一种高效、选择性的CDK8/19抑制剂，具有低清除率和中等口服药代动力学特性。
| Cas No. | 2648453-53-4 |
| 分子式 | C22H22ClN7O |
| 分子量 | 435.91 |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | JH-XVI-178 is a highly potent and selective inhibitor of CDK8/19 that displays low clearance and moderate oral pharmacokinetic properties. [1]. Hatcher JM, et al. Development of Highly Potent and Selective Pyrazolopyridine Inhibitor of CDK8/19. ACS Med Chem Lett. 2021 Oct 22;12(11):1689-1693. |
