LRRK2 inhibitor 1 是有效，选择性的 LRRK2 抑制剂，IC50 为 6.8。
| Cas No. | 1802525-61-6 |
| 分子式 | C20H23N5O4 |
| 分子量 | 397.43 |
| 溶解度 | DMSO : 62.5 mg/mL (157.26 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | LRRK2 inhibitor 1 is a potent, selective and oral LRRK2 inhibitor with an pIC50 of 6.8. [1]. Ding X, et al. Discovery of 4-ethoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amines as potent, selective and orally bioavailable LRRK2 inhibitors. Bioorg Med Chem Lett. 2018 May 15;28(9):1615-1620. |
