VEGFR-2-IN-29 (Compound 5) 是一种 VEGFR-2 抑制剂,IC50 为 16.5 nM。
Cas No. | 62802-77-1 |
分子式 | C16H11N3O3 |
分子量 | 293.28 |
溶解度 | DMSO : 20 mg/mL (68.19 mM; ultrasonic and warming and heat to 60°C) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | VEGFR-2-IN-29 (Compound 5) is aVEGFR-2inhibitor with anIC50of 16.5 nM[1]. VEGFR-2-IN-29 (Compound 5) (72 h) inhibits HUVEC proliferation[1]. Cell Proliferation Assay[1] Cell Line: | HUVEC | Concentration: | | Incubation Time: | 72 h | Result: | Showed inhibition with IC50s of 15.8 nM and 210 nM against VEGF- and bFGF-induced HUVEC proliferation. |
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