Mavrilimumab (CAM 3001) 是一种单克隆抗体，可与粒细胞-巨噬细胞集落刺激因子 (GM-CSF) 受体的 α 亚基结合，并阻断 GM-CSF 下游细胞内信号传导。GM-CSF 可能是与呼吸衰竭和死亡相关的过度活跃炎症反应的介质。
| Cas No. | 1085337-57-0 |
| 别名 | CAM 3001 |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor (GM-CSF) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death[1]. |
