GSK299423 or GlaxoSmithKline 299423 is an antibiotic chemical compound that has been identified as potentially effective in treating patients infected with bacteria expressing the New Delhi metallo-beta-lactamase. The antibiotic inhibits the enzyme topoisomerase, which bacteria need to replicate. References: Mudeppa DG, Kumar S, Kokkonda S, White J, Rathod PK. Topoisomerase II from
Human Malaria Parasites: EXPRESSION, PURIFICATION, AND SELECTIVE INHIBITION. J
Biol Chem. 2015 Aug 14;290(33):20313-24. doi: 10.1074/jbc.M115.639039. Epub 2015
Jun 8. PubMed PMID: 26055707; PubMed Central PMCID: PMC4536438.
纯度:≥98%
CAS:1352149-24-6