SNU-BP is an agonist of PPAR-gamma, inhibiting lipopolysaccharide (LPS)-induced NO production and pro-inflammatory cytokines. SNU-BP potentiates interleukin-4-induced arginase-1 expression, and promotes microglial polarization toward an M2 anti-inflammatory phenotype. References: Song GJ, Nam Y, Jo M, Jung M, Koo JY, Cho W, Koh M, Park SB, Suk K. A novel
small-molecule agonist of PPAR-γ potentiates an anti-inflammatory M2 glial
phenotype. Neuropharmacology. 2016 Oct;109:159-169. doi:
10.1016/j.neuropharm.2016.06.009. Epub 2016 Jun 8. PubMed PMID: 27288982.
纯度:≥98%
CAS:1621513-98-1