基因名:
GFRAL
产品别名:
C6orf144; GRAL; UNQ9356; bA360D14.1; GFRAL; GDNF family receptor alpha like; GDNF family receptor alpha like; GDNF family receptor alpha-like; IVFI9356; GFRAL蛋白; 胶质细胞系源性神经营养因子受体α1样蛋白;
背景信息:
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses