基因名：
Macc1
产品别名：
4732474O15Rik； Gm267； Macc1； metastasis associated in colon cancer 1； metastasis associated in colon cancer 1； metastasis-associated in colon cancer protein 1； 结肠癌转移关联基因1(MACC1)； 结肠癌转移相关蛋白1；
背景信息：
MACC1 is a key regulator of the hepatocyte growth factor(HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed19098908]).[supplied by OMIM].
