基因名：
DIRAS1
产品别名：
Di-Ras1； GBTS1； RIG； DIRAS1； DIRAS family GTPase 1； DIRAS family GTPase 1； GTP-binding protein Di-Ras1； DIRAS family, GTP-binding RAS-like 1； distinct subgroup of the Ras family member 1； ras-related inhibitor of cell growth； small GTP-binding tumor suppressor 1； RAS相关抑细胞生长蛋白1；
背景信息：
The three human RAS genes encode highly related 188 to 189 amino acid proteins, designated H-Ras, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing). Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis. DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. It is highly expressed in heart and brain.
