基因名：
UPRT
产品别名：
FUR1； UPP； UPRT； uracil phosphoribosyltransferase homolog； uracil phosphoribosyltransferase homolog； uracil phosphoribosyltransferase homolog； RP11-311P8.3； UMP pyrophosphorylase； UPRTase； uracil phosphoribosyltransferase (FUR1) homolog； 尿嘧啶磷酸核糖转移酶(UPRT)；
背景信息：
UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. UPRT is a potential target for rational design of drugs to treat parasitic infections and cancer
