基因名：
DTNBP1
产品别名：
BLOC1S8； DBND； HPS7； My031； SDY； DTNBP1； dystrobrevin binding protein 1； dystrobrevin binding protein 1； dysbindin； BLOC-1 subunit 8； Hermansky-Pudlak syndrome 7 protein； biogenesis of lysosomal organelles complex-1, subunit 8； biogenesis of lysosome-related organelles complex 1 subunit 8； dysbindin-1； 异连蛋白结合蛋白1(DTNBP1)； 精神分裂症易感基因；
背景信息：
Dysbindin may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC1), and binds to alpha and beta dystrobrevins, which are components of the dystrophin associated protein complex (DPC). Mutations in Dysbindin gene are associated with Hermansky-Pudlak syndrome type 7. Dysbindin gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
