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重组感觉神经性耳聋常染色体隐性遗传61蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

Recombinant Slc26a5
Recombinant solute carrier family 26, member 5 protein
基因名:

Slc26a5


产品别名:

Pres; prestin; Slc26a5; solute carrier family 26, member 5; solute carrier family 26, member 5; prestin; outer hair cell motor protein; prestin (motor protein); 感觉神经性耳聋常染色体隐性遗传61;


背景信息:
This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]
 
 
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