基因名：
STN1
产品别名：
AAF-44； AAF44； OBFC1； RPA-32； bA541N10.2； STN1； STN1 subunit of CST complex； STN1 subunit of CST complex； CST complex subunit STN1； STN1, CST complex subunit； alpha accessory factor 44； oligonucleotide/oligosaccharide binding fold containing 1； oligonucleotide/oligosaccharide-binding fold-containing protein 1； replication protein A 32 kDa subunit； suppressor of cdc thirteen homolog； α辅助因子44；
背景信息：
CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
