基因名：
Top1mt
产品别名：
2900052H09Rik； Top1mt； DNA topoisomerase 1, mitochondrial； DNA topoisomerase 1, mitochondrial； DNA topoisomerase I, mitochondrial； mitochondrial topoisomerase I； 线粒体DNA拓普西异构酶Ⅰ；
背景信息：
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012].
