基因名：
Cenpu
产品别名：
1700029A22Rik； Mlf1ip； Cenpu； centromere protein U； centromere protein U； centromere protein U； CENP-U； MLF1-interacting protein； myeloid leukemia factor 1 interacting protein； 髓细胞性白血病蛋白1；
背景信息：
Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
