基因名:
Dock7
产品别名:
3110056M06Rik; Gm430; Dock7; dedicator of cytokinesis 7; dedicator of cytokinesis 7; dedicator of cytokinesis protein 7; protein moonlight; 胞质分裂专一蛋白7; 胞质分裂作用因子7(DOCK7);
背景信息:
DOCK 7 is a 2,140 amino acid protein that localizes to developing axons and contains one DHR-1 domain and one DHR-2 domain. Expressed in a variety of tissues, DOCK 7 functions as a guanine nucleotide exchange factor (GEF) that specifically activates Rac 1 and Rac 3 by catalyzing the exchange of bound GDP for free GTP. Multiple isoforms of DOCK 7 exist due to alternative splicing events.