重组3'-5'外切酶1蛋白

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重组3'-5'外切酶1蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

重组核糖核酸外切酶1(ERI1)蛋白
Recombinant Eri1

基因名：

Eri1

产品别名：

3'hexo； 3110010F15Rik； Thex1； eri-1； Eri1； exoribonuclease 1； exoribonuclease 1； 3'-5' exoribonuclease 1； 3'-5' exonuclease ERI1； enhanced RNAi protein 1； eri-1 homolog； histone mRNA 3' end-specific exonuclease； histone mRNA 3'-exonuclease 1； three prime histone mRNA exonuclease 1； 3'-5'外切酶1蛋白；核糖核酸外切酶1(ERI1)；

背景信息：

Helicase with RNase motif, more commonly designated Dicer, cleaves double-stranded RNA (dsRNA) in the RNA interference and small temporal RNA (stRNA) pathways, producing active small RNA components (siRNAs) which target the destruction of RNA and repress gene expression. Human Dicer cleaves dsRNA independent of ATP. The 3’-5’ exonuclease ERI-1, also known as Protein 3'hExo, degrades Histone mRNA after replication and may be involved in the regulation of RNA interference. ERI-1 has a high affinity for the stem-loop structure of replication-dependent Histone pre-mRNAs. It requires the 5'-ACCCA-3' sequence present in stem-loop structure. ERI-1 and a stem-loop binding protein (SLBP) target opposite faces of a unique highly conserved stem-loop RNA scaffold towards the 3' end of Histone mRNA.