基因名:
Apoa5
产品别名:
1300007O05Rik; Apoav; RAP3; Apoa5; apolipoprotein A-V; apolipoprotein A-V; apolipoprotein A-V; apolipoprotein A5; regeneration-associated protein 3; 载脂蛋白A5; 载脂蛋白A5(APOA5);
背景信息:
The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009].