基因名:
Ilkap
产品别名:
Ilkap; ILK associated serine/threonine phosphatase; ILK associated serine/threonine phosphatase; integrin-linked kinase-associated serine/threonine phosphatase 2C; PP2Cdelta; protein phosphatase 2C; 整合素连接激酶相关丝氨酸/苏氨酸磷酸酶;
背景信息:
ILKAP belongs to the PP2C family and contains one PP2C-like domain. ILKAP has been suggested to inhibit oncogenic transformation and the ILK-GSK3beta signaling axis, and can bind two magnesium or manganese ions per subunit as cofactors. The gene encoding ILKAP maps to human chromosome 2, which consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome.