基因名：
Cd200r1
产品别名：
CD200R； Mox2r； OX2R； Cd200r1； CD200 receptor 1； CD200 receptor 1； cell surface glycoprotein CD200 receptor 1； CD200 cell surface glycoprotein receptor； Orexin receptor 2； antigen identified by monoclonal antibody MRC OX-2 receptor； cell surface glycoprotein OX2 receptor 1； CD200受体； CD200受体1(CD200R1)；
背景信息：
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal.
