基因名：
PREX1
产品别名：
P-REX1； PREX1； phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1； phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1； phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein； PIP3 dependent Rac exchange factor 1； ptdIns(3,4,5)-dependent Rac exchanger 1； PREX1蛋白；
背景信息：
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008]
