基因名：
HACE1
产品别名：
SPPRS； HACE1； HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1； HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1； E3 ubiquitin-protein ligase HACE1； HECT-type E3 ubiquitin transferase HACE1； E3泛素蛋白连接酶HACE1；
背景信息：
This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016]
