基因名:
PMEPA1
产品别名:
STAG1; TMEPAI; PMEPA1; prostate transmembrane protein, androgen induced 1; prostate transmembrane protein, androgen induced 1; protein TMEPAI; solid tumor-associated 1 protein; transmembrane, prostate androgen induced RNA; 跨膜前列腺雄激素诱导蛋白1;
背景信息:
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]