基因名：
ANKS1B
产品别名：
AIDA； AIDA-1； ANKS2； EB-1； EB1； cajalin-2； ANKS1B； ankyrin repeat and sterile alpha motif domain containing 1B； ankyrin repeat and sterile alpha motif domain containing 1B； ankyrin repeat and sterile alpha motif domain-containing protein 1B； E2a-Pbx1-associated protein； amyloid-beta precursor protein intracellular domain associated protein 1； cajalin 2； β淀粉样蛋白胞内结构域相关蛋白1；
背景信息：
The β-Amyloid protein precursor (AbPP) is a widely expressed transmembrane protein that is processed into the b-Amyloid (Ab) peptide, which accumulates in insoluble plaques in the brain of Alzheimer’s disease patients and AbPP intracellular domain (AID). AID may function as a pro-apoptotic peptide, a regulator of calcium homeostasis and a molecule involved in transcriptional regulation. The AID associated protein 1 (AIDA-1) is highly expressed in the brain and is regulated by AbPP. It interacts with AbPP to play a role in brain development. AIDA-1 also interacts with coilin in Cajal bodies to regulate pre-mRNA splicing.
