基因名：
HDAC8
产品别名：
CDA07； CDLS5； HD8； HDACL1； KDAC8； MRXS6； RPD3； WTS； HDAC8； histone deacetylase 8； histone deacetylase 8； histone deacetylase 8； histone deacetylase-like 1； protein deacetylase HDAC8； protein decrotonylase HDAC8； 磷酸化组蛋白去乙酰化酶8； 组蛋白去乙酰化酶8； 组蛋白脱乙酰基酶8(HDAC8)；
背景信息：
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
