重组泛素蛋白连接酶W

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重组泛素蛋白连接酶W

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Recombinant UBE2W
Recombinant ubiquitin conjugating enzyme E2 W protein

基因名：

UBE2W

产品别名：

UBC-16； UBC16； UBE2W； ubiquitin conjugating enzyme E2 W； ubiquitin conjugating enzyme E2 W； ubiquitin-conjugating enzyme E2 W； E2 ubiquitin-conjugating enzyme W； N-terminal E2 ubiquitin-conjugating enzyme； N-terminus-conjugating E2； ubiquitin carrier protein W； ubiquitin conjugating enzyme E2 W (putative)； ubiquitin conjugating enzyme E2W (putative)； ubiquitin-conjugating enzyme 16； ubiquitin-conjugating enzyme 2W； ubiquitin-protein ligase W；泛素蛋白连接酶W；

背景信息：

Ube2W is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It has been shown to catalyze monoubiquitination of Fanconi anemia complementation group L (FANCL), an E3 Ub ligase. The FANCL is part of a complex that is able to monoubiquitinate FANCD2 during DNA repair. Ube2W can also interact with the RING domain of the breast and ovarian cancer susceptibility protein called BRCA1.