基因名：
AGGF1
产品别名：
GPATC7； GPATCH7； HSU84971； HUS84971； VG5Q； AGGF1； angiogenic factor with G-patch and FHA domains 1； angiogenic factor with G-patch and FHA domains 1； angiogenic factor with G patch and FHA domains 1； G patch domain-containing protein 7； angiogenic factor VG5Q； vasculogenesis gene on 5q protein； G补缀FHA域血管生成因子1(AGGF1)； 血管生长因子VG5Q；
背景信息：
Angiogenic factors are critical to the initiation of angiogenesis and maintenance of the vascular network. VG5Q protein acts as a potent angiogenic factor in promoting angiogenesis, and suppression of VG5Q expression inhibits vessel formation. VG5Q shows strong expression in blood vessels and is secreted as vessel formation is initiated. VG5Q can bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. It also interacts with another secreted angiogenic factor, TWEAK (also known as TNFSF12). VG5Q is defective in patients with the vascular disease Klippel-Trenaunay syndrome (KTS).
