基因名：
UACA
产品别名：
NUCLING； UACA； uveal autoantigen with coiled-coil domains and ankyrin repeats； uveal autoantigen with coiled-coil domains and ankyrin repeats； uveal autoantigen with coiled-coil domains and ankyrin repeats； nuclear membrane binding protein； 卷曲域锚蛋白重复序列葡萄膜自身抗原(UACA)； 葡萄膜自身抗原Uaca；
背景信息：
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation,LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation.Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1.Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility.Interaction with ARF6 may modulate cell shape and motility after injury.
