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重组发育相关蛋白ERCC6L/乙醇致畸因子
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

Recombinant ERCC6L
Recombinant ERCC excision repair 6 like, spindle assembly checkpoint helicase protein
基因名:

ERCC6L


产品别名:

PICH; RAD26L; ERCC6L; ERCC excision repair 6 like, spindle assembly checkpoint helicase; ERCC excision repair 6 like, spindle assembly checkpoint helicase; DNA excision repair protein ERCC-6-like; ATP-dependent helicase ERCC6-like; Plk1-interacting checkpoint helicase; SNF2/RAD54 family protein; excision repair cross-complementation group 6 like; excision repair cross-complementing rodent repair deficiency complementation group 6 - like; excision repair cross-complementing rodent repair deficiency, complementation group 6-like; excision repair protein ERCC6-like; tumor antigen BJ-HCC-15; 发育相关蛋白ERCC6L/乙醇致畸因子;


背景信息:
ERCC6L belongs to the SNF2 ATPase family and acts as an essential component of the spindle assembly checkpoint. It contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. It acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. ERCC6L may also play a role in the teratogenic action of alcohol.
 
 
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