基因名:
IL20RA
产品别名:
CRF2-8; IL-20R-alpha; IL-20R1; IL-20RA; IL20RA; interleukin 20 receptor subunit alpha; interleukin 20 receptor subunit alpha; interleukin-20 receptor subunit alpha; class II cytokine receptor ZCYTOR7; cytokine receptor family 2 member 8; interleukin 20 receptor alpha subunit; interleukin 20 receptor, alpha; interleukin-20 receptor I; 白介素20受体α(IL20Ra); 白介素20受体α链蛋白;
背景信息:
Interleukin-20 Receptor Subunit α (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide, a 221 amino acid extracellular domain with two fibronectin type-III domains, a 24 amino acid transmembrane region, and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB, and the complex serves as a receptor for IL19, IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.