基因名:
Cdca8
产品别名:
4831429J16Rik; AU044747; BOR; Borealin; D4Ertd421e; DasraB; MESRGP; Cdca8; cell division cycle associated 8; cell division cycle associated 8; borealin; MESrg; cell division cycle-associated protein 8; embryonic stem cell-related; 细胞分裂周期蛋白8;
背景信息:
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.